Call Us

Contact Us

Gastroscopy Complications: Recognizing and Managing Potential Risks

woman sitting in bed with stomach pain

Gastroscopy, also known as esophagogastroduodenoscopy (EGD), is a valuable diagnostic procedure that allows healthcare professionals to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and duodenum. It is commonly used to investigate symptoms such as persistent heartburn, difficulty swallowing, abdominal pain, and unexplained weight loss.

While gastroscopy is generally considered safe and well-tolerated, like any medical procedure, it carries potential risks. In this article, we will explore the complications that may arise during or after gastroscopy, as well as strategies to recognize and manage these risks.

Understanding Gastroscopy

What is Gastroscopy?

Gastroscopy is a medical procedure that involves the use of a thin, flexible tube with a light and camera (gastroscope) to examine the upper GI tract. The scope is inserted through the mouth and gently advanced into the esophagus, stomach, and duodenum, allowing the doctor to visualize the lining of these organs and diagnose various conditions.

Indications for Gastroscopy

Gastroscopy is utilized to investigate a range of gastrointestinal symptoms, such as:

  • Chronic or recurring heartburn (acid reflux)
  • Difficulty or pain when swallowing (dysphagia)
  • Unexplained weight loss
  • Persistent abdominal pain
  • Gastrointestinal bleeding
  • Anemia of unknown origin

Potential Complications of Gastroscopy

While gastroscopy is generally safe, there are potential risks associated with the procedure:

  • Perforation. The most serious complication of gastroscopy is perforation, where the scope inadvertently punctures the wall of the esophagus, stomach, or duodenum. This can lead to leakage of stomach contents into the abdominal cavity, resulting in a potentially life-threatening condition called peritonitis.
  • Bleeding. During the insertion of the gastroscope or during tissue sampling (biopsies), there is a slight risk of causing bleeding. In most cases, any bleeding is minimal and stops spontaneously. However, excessive bleeding may require further interventions.
  • Aspiration. Aspiration occurs when stomach contents enter the respiratory tract, leading to potential lung infection. While the risk is low, it is higher in individuals with certain medical conditions, such as a history of aspiration, difficulty swallowing, or compromised gag reflex.
  • Reaction to Anesthesia or Sedation. Gastroscopy is typically performed under sedation or general anesthesia. Some individuals may have adverse reactions to these medications, though serious complications are rare.
  • Infection. Infection is a possible risk, although the gastroscope is cleaned and disinfected thoroughly according to strict guidelines to minimize this risk.
  • Minor Discomfort and Side Effects. After the procedure, patients may experience some mild discomfort, such as a sore throat or bloating. These side effects usually resolve quickly.

Recognizing Complications During Gastroscopy

  • Persistent Pain or Discomfort. Mild discomfort and bloating are common after gastroscopy, but if the pain persists or becomes severe, it could indicate a potential complication, such as perforation or bleeding.
  • Abnormal Bleeding. Minor bleeding during gastroscopy, such as from biopsies, is normal and typically stops on its own. However, excessive or prolonged bleeding requires immediate attention.
  • Difficulty Breathing or Chest Pain. These symptoms may indicate aspiration or an adverse reaction to anesthesia, and medical attention should be sought immediately.
  • Fever or Signs of Infection. A fever, increased redness, swelling, or discharge at the site of the gastroscopy could be signs of infection and should be reported to the healthcare provider.

Managing and Preventing Complications

  • Choose an Experienced Healthcare Provider. Selecting a skilled and experienced endoscopist is crucial in reducing the risk of complications during gastroscopy. They will be better equipped to handle any unexpected issues that may arise during the procedure.
  • Inform the Healthcare Provider of Relevant Medical History. Before the procedure, provide a detailed medical history to the healthcare provider, including any previous adverse reactions to anesthesia or sedation, dental issues such as loose teeth, types of medications being taken, and pre-existing medical conditions.
  • Follow Pre-Procedure Instructions Thoroughly. Adhering to pre-procedure guidelines, such as fasting requirements and medication adjustments, is essential to ensure a successful and safe gastroscopy.
  • Monitor Vital Signs During and After the Procedure. Healthcare providers should continuously monitor the patient’s vital signs during the procedure and in the immediate post-procedure period to promptly identify any signs of distress or complications.
  • Provide Clear Post-Procedure Instructions. Patients should receive clear post-procedure instructions, including potential side effects, what to do if complications arise, and when to seek immediate medical attention.
  • Adherence to Infection Control Measures. Healthcare facilities must follow strict infection control protocols to prevent the risk of infections during gastroscopy. This includes thorough cleaning and disinfection of all endoscopes and associated equipment between procedures.
  • Proper Training and Accreditation. Medical professionals performing gastroscopy should undergo comprehensive training and obtain proper accreditation in endoscopy. Regular competency assessments and continuing education ensure they stay up-to-date with the latest techniques and safety practices.
  • Patient Education and Informed Consent. Before the procedure, healthcare providers should inform patients about the potential risks and benefits of gastroscopy, as well as alternative options. Obtaining informed consent from the patient ensures they are aware of the procedure’s potential complications.
  • Careful Monitoring During the Procedure. During gastroscopy, healthcare providers should closely monitor patients’ vital signs and response to sedation or anesthesia. Early recognition of any adverse reactions allows for timely interventions.
  • Individualized Risk Assessment. Each patient’s risk factors and medical history should be carefully evaluated to determine the most appropriate sedation or anesthesia for the procedure. For individuals with certain health conditions, alternative sedation options may be considered.
  • Post-Procedure Follow-Up. After gastroscopy, patients should receive adequate post-procedure care and instructions. This includes information about expected side effects, any signs of complications to watch out for, and whom to contact in case of concerns.
  • Quality Assurance and Monitoring. Healthcare facilities should establish a robust quality assurance program to review gastroscopy outcomes, identify potential areas for improvement, and implement measures to enhance patient safety.
  • Risk Stratification and Patient Safety. It’s important to recognize that the risk of complications during gastroscopy can vary depending on individual factors, such as age, overall health, and the indication for the procedure. Patients with certain medical conditions, such as heart or lung diseases, may have an increased risk of complications, and their care should be tailored accordingly.

For patients at higher risk, healthcare providers may consider alternatives to traditional sedation, such as using lighter sedation or avoiding sedation altogether if feasible. However, it is essential to balance patient comfort with safety and the quality of the procedure.


Gastroscopy is a valuable diagnostic tool in the investigation of upper gastrointestinal conditions. While it is generally safe and well-tolerated, it is not without potential complications. Recognizing and managing these risks is essential for ensuring patient safety and positive outcomes.

By adhering to infection control measures, providing comprehensive patient education, monitoring patients closely during and after the procedure, and individualizing care based on risk factors, healthcare providers can minimize the risk of complications during gastroscopy.

For individuals scheduled to undergo gastroscopy, it is essential to communicate openly with their healthcare providers about any medical conditions, medications, or concerns they may have. This collaborative approach ensures that patients are well-informed, comfortable, and receive the highest standard of care during the procedure.

Ultimately, gastroscopy remains an invaluable tool in diagnosing and treating gastrointestinal conditions, and with careful attention to patient safety, it can continue to be a safe and effective procedure for patients of all ages.

Introducing Curasia Endoscopy Centre

Our host, Jerald Foo, will be taking you to our first centre at Jurong East.

Make An Enquiry

Leave us your details and we’ll get back to you shortly.
Prefer to talk? Call our clinic directly to make an enquiry at +65 6679 1229

or Whatsapp us at +65 9750 8783

We are available 24 hours

Let's Get in Touch!

Clinic Details

Other Related Articles

Curasia Endoscopy

Call Us

Contact Us