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Gastroscopy in Pregnancy: Navigating the Safety Landscape

pregnant woman being examined by a doctor and a nurse

Gastroscopy, a diagnostic procedure involving the insertion of a thin, flexible tube with a light and camera into the stomach, is a valuable tool for investigating gastrointestinal issues. However, when it comes to performing gastroscopy during pregnancy, healthcare providers must carefully navigate the safety landscape to ensure the well-being of both the mother and the developing fetus. 

In this article, we will explore the considerations, risks, and safety measures associated with gastroscopy in pregnancy.


Gastroscopy is a medical procedure used to visualize and examine the lining of the stomach and upper gastrointestinal tract. While it is generally considered safe for most individuals, performing gastroscopy during pregnancy introduces unique challenges and requires a nuanced approach to balance diagnostic needs and maternal-fetal safety.

Indications for Gastroscopy in Pregnancy

Gastroscopy during pregnancy is typically reserved for specific indications where the potential benefits outweigh the risks. Common reasons for performing gastroscopy in pregnant individuals include:

Persistent Gastrointestinal Symptoms

If a pregnant woman experiences persistent symptoms such as abdominal pain, nausea, vomiting, or difficulty swallowing, gastroscopy may be recommended to identify the underlying cause.

Gastrointestinal Bleeding

In cases of gastrointestinal bleeding, gastroscopy is a valuable tool for locating the source of bleeding and determining the appropriate course of action.

Suspected Ulcers or Tumors

Suspected stomach ulcers or tumors may warrant a gastroscopic examination to provide accurate diagnosis and inform treatment decisions.

Timing Considerations

Timing is crucial when contemplating gastroscopy during pregnancy. Healthcare providers often aim to conduct the procedure during the second trimester when the risks to the developing fetus are relatively lower. However, urgent cases may necessitate gastroscopy during the first or third trimester.

Second Trimester Preference

The second trimester is generally considered the safest time for gastroscopy during pregnancy. At this stage, the fetus has passed the critical developmental phases of the first trimester, and the risk of spontaneous miscarriage is reduced.

Urgent Cases in Other Trimesters

In urgent situations where gastroscopy is essential for diagnosis and management, healthcare providers may carefully weigh the risks and benefits, considering the specific circumstances of the patient.

Risks and Considerations

Performing gastroscopy during pregnancy involves potential risks that healthcare providers must carefully assess and communicate to the expectant mother.

  • Risk of Aspiration. The risk of aspiration, where stomach contents enter the lungs, is a concern during gastroscopy. Pregnant women are more prone to reflux due to hormonal changes, increasing the risk of aspiration.
  • Sedation Considerations. The use of sedation during gastroscopy requires careful consideration. While certain sedatives are considered safe during pregnancy, their use must be minimized, and the benefits must outweigh potential risks.
  • Positioning Challenges. Gastroscopy typically requires the patient to lie on their left side, which can be challenging and uncomfortable for pregnant women, especially in later stages of pregnancy.

Safety Measures and Precautions

To mitigate risks and ensure the safety of both the mother and the fetus during gastroscopy in pregnancy, healthcare providers implement specific safety measures and precautions.

Careful Sedation Selection

Healthcare providers opt for sedatives that have a proven safety profile during pregnancy. Medications such as propofol may be chosen due to their rapid onset and short duration, minimizing fetal exposure.

Continuous Monitoring

Continuous monitoring of vital signs, including heart rate, blood pressure, and oxygen saturation, is essential during gastroscopy to promptly identify and address any complications.

  • Shortened Procedure Duration. Minimizing the duration of the gastroscopic procedure helps reduce the time of exposure to sedatives and anesthesia, contributing to overall safety.
  • Use of Local Anesthesia. Local anesthesia may be employed to numb the back of the throat, reducing the need for deeper sedation and minimizing the impact on the fetus.
  • Lateral Tilt Positioning. To alleviate pressure on the vena cava and improve blood flow to the uterus, pregnant women undergoing gastroscopy may be positioned in a left lateral tilt, especially in later stages of pregnancy.

Patient Counseling and Informed Consent

Transparent communication with the expectant mother is paramount when considering gastroscopy during pregnancy. Adequate counseling and obtaining informed consent are crucial components of the process.

  • Discussion of Risks and Benefits. Healthcare providers should engage in thorough discussions with pregnant patients, outlining the potential risks and benefits of gastroscopy and addressing any concerns or questions.
  • Informed Consent. Obtaining informed consent involves ensuring that the patient fully understands the nature of the procedure, potential risks, alternative options, and the implications for the pregnancy.

Alternatives and Non-Invasive Diagnostics

In certain situations, non-invasive diagnostic methods or alternative procedures may be considered to avoid the potential risks associated with gastroscopy during pregnancy.

  • Ultrasound and Imaging. Non-invasive imaging techniques, such as ultrasound, may be utilized to gather diagnostic information without the need for invasive procedures.
  • Alternative Endoscopic Procedures. Depending on the specific clinical scenario, alternative endoscopic procedures with lower associated risks may be considered as viable options.

Post-Procedure Monitoring and Care

Post-gastroscopy care for pregnant individuals involves monitoring for potential complications and ensuring the well-being of both the mother and the fetus.

Observation Period

After the procedure, pregnant patients may be observed for a period to monitor for any adverse effects or complications.

Communication of Findings

Healthcare providers should promptly communicate the findings of the gastroscopy to the patient, providing insights into the diagnosis and outlining any recommended follow-up care.


Gastroscopy during pregnancy requires a thoughtful and cautious approach, considering the specific risks and challenges associated with this diagnostic procedure. While it may be necessary in certain clinical scenarios, healthcare providers must carefully weigh the potential benefits against the risks, prioritize safety measures, and engage in transparent communication with the expectant mother.

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